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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCC1
All Species:
22.42
Human Site:
S405
Identified Species:
41.11
UniProt:
P18754
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18754
NP_001041659.1
421
44969
S405
N
R
V
V
L
S
V
S
S
G
G
Q
H
T
V
Chimpanzee
Pan troglodytes
XP_001152659
421
44920
S405
N
R
V
V
L
S
V
S
S
G
G
Q
H
T
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544458
630
67681
S614
N
R
V
V
L
S
V
S
S
G
G
Q
H
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE37
421
44912
S405
N
R
V
V
L
T
V
S
S
G
G
Q
H
T
V
Rat
Rattus norvegicus
NP_001121661
421
45093
S405
N
R
E
V
L
T
V
S
S
G
G
Q
H
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_427366
194
21051
R179
Y
F
T
F
A
I
T
R
E
G
H
I
Y
G
F
Frog
Xenopus laevis
P25183
424
45052
V409
E
D
R
E
V
L
S
V
S
S
G
G
Q
H
T
Zebra Danio
Brachydanio rerio
Q6NYE2
495
54133
Q475
H
S
L
V
I
A
R
Q
D
T
E
Q
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25171
547
58832
S405
G
K
H
M
L
L
A
S
G
G
G
Q
H
A
I
Honey Bee
Apis mellifera
XP_394158
439
46956
A418
G
K
T
V
V
R
V
A
G
G
G
Q
H
T
L
Nematode Worm
Caenorhab. elegans
Q18211
569
61466
A545
K
P
E
E
I
S
S
A
H
L
D
G
Y
S
I
Sea Urchin
Strong. purpuratus
XP_001191815
424
45249
K409
L
E
T
K
K
A
V
K
V
A
S
G
G
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21827
482
52995
S463
C
G
G
Q
F
S
V
S
G
G
V
K
L
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
64.7
N.A.
93.8
93.3
N.A.
N.A.
37
75.9
22.2
N.A.
29
45.5
29.5
52.8
Protein Similarity:
100
99.7
N.A.
65.8
N.A.
96.9
96.6
N.A.
N.A.
42
85.6
40
N.A.
43.6
63
42.5
70.7
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
N.A.
6.6
13.3
13.3
N.A.
40
46.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
N.A.
13.3
20
40
N.A.
60
73.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
16
8
16
0
8
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
8
% D
% Glu:
8
8
16
16
0
0
0
0
8
0
8
0
8
0
8
% E
% Phe:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
8
8
0
0
0
0
0
24
70
62
24
8
8
0
% G
% His:
8
0
8
0
0
0
0
0
8
0
8
0
54
8
8
% H
% Ile:
0
0
0
0
16
8
0
0
0
0
0
8
0
0
16
% I
% Lys:
8
16
0
8
8
0
0
8
0
0
0
8
0
8
0
% K
% Leu:
8
0
8
0
47
16
0
0
0
8
0
0
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
0
62
8
8
0
% Q
% Arg:
0
39
8
0
0
8
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
39
16
54
47
8
8
0
0
16
0
% S
% Thr:
0
0
24
0
0
16
8
0
0
8
0
0
0
47
8
% T
% Val:
0
0
31
54
16
0
62
8
8
0
8
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _